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1.
J Water Health ; 21(6): 763-770, 2023 Jun.
Article in English | MEDLINE | ID: covidwho-2328286

ABSTRACT

Many previous studies have already pointed out that health concerns influence people's choice of drinking water. The health concerns discussed in the preceding studies are those that are associated with the choice of a particular type of water. On the other hand, people also experience health concerns in their daily lives, unrelated to the choice of drinking water. These two need to be discussed separately, but preceding studies have failed to make a distinction. In this study, we refer to the former as 'health concerns attributable to water characteristics' and the latter as 'health concerns stemming from personality traits.' The purpose of this study is to explore the relationship, if any, between people's health concerns stemming from personality traits and their choice of drinking water. We use three types of health concerns that are stemming from personality traits (e.g. health maintenance, pesticide residues in food, and COVID-19 infection) to elucidate their influences on the choice of drinking water. Based on the results of the analysis, this study reveals that the influence of health concerns stemming from personality traits on the choice of drinking water differs depending on its typology.


Subject(s)
COVID-19 , Drinking Water , Humans , COVID-19/epidemiology , Pandemics , Tokyo/epidemiology , Personality
2.
Environ Sci Pollut Res Int ; 30(28): 72284-72307, 2023 Jun.
Article in English | MEDLINE | ID: covidwho-2312191

ABSTRACT

The COVID-19 pandemic and sudden lockdown have severely hampered the country's economic growth and socio-cultural activities while imparting a positive effect on the overall fitness of the environment especially air and water resources. Increased urbanization and rapid industrialization have led to rising pollution and deterioration of rivers and associated sectors such as agriculture, domestic and commercial needs. However, various available studies in different parts of the country indicate that the COVID-19 pandemic has changed the entire ecosystem. But it is noted that studies are lacking in the southern Western Ghats region of India. Therefore, the present study attempts to investigate how the continuous lockdowns affect the River Water Quality (RWQ) during lockdown (October 2020) and post-lockdown (January 2021) periods in the lower catchments (Eloor-Edayar industrialized belt) of Periyar river, Kerala state, South India. A total of thirty samples (15 samples each) were analyzed based on drinking water quality, irrigational suitability, and multivariate statistical methods to evaluate the physical and chemical status of RWQ. The results of the Water Quality Index (WQI) for assessing the drinking water suitability showed a total of 93% of samples in the excellent and good category during the lockdown, while only 47% of samples were found fit for drinking during the post-lockdown period. Irrigational suitability indices like Mg hazard, KR, PI, SAR, and Wilcox diagram revealed lockdown period samples as more suitable for irrigational activities compared to post-lockdown samples with site-specific changes. Spearman rank correlation analysis indicated EC and TDS with a strong positive correlation to Ca2+, Mg2+, Na+, K+, TH, SO42-, and Cl- during both periods as well as strong positive correlations within the alkaline earth elements (Ca2+ and Mg 2+) and alkalis (Na+ and K+). Three significant components were extracted from principal component analysis (PCA), explaining 88.89% and 96.03% of the total variance for lockdown and post-lockdown periods, respectively. Variables like DO, BOD, Ca2+, NO3-, and Cl- remained in the same component loading during both periods elucidating their natural origin in the basin. The results of health risk assessment based on US EPA represented hazard quotient and hazard index values below the acceptable limit signifying no potential noncarcinogenic risk via oral exposure except As, suggesting children as more vulnerable to the negative effects than adults. Furthermore, this study also shows rejuvenation of river health during lockdown offers ample scope to policymakers, administrators and environmentalists for deriving appropriate plans for the restoration of river health from anthropogenic stress.


Subject(s)
COVID-19 , Drinking Water , Groundwater , Water Pollutants, Chemical , Child , Humans , Water Quality , Rivers , Environmental Monitoring/methods , Drinking Water/analysis , Ecosystem , Pandemics , Communicable Disease Control , Environmental Health , India , Water Pollutants, Chemical/analysis
3.
Front Public Health ; 11: 1063052, 2023.
Article in English | MEDLINE | ID: covidwho-2250692

ABSTRACT

Background: Access to water, sanitation, and hygiene is an important element for communicable disease control including the existing COVID-19 pandemic. This is due to the growing water demand and decreasing water availability, because of shrinking resources, increased urbanization, and pollution. This problem is higher, particularly among least developed countries like Ethiopia. This study, therefore, aimed at investigating the level of improved water sources and sanitation as well as their predictors in Ethiopia using EMDHS-2019. Method: Mini Ethiopian Demographic and Health Surveys 2019 database survey was used in this study. Data collection took place over 3 months, from 21 March 2019 to 28 June 2019. A total of 9,150 households were selected for the sample, of which 8,794 were engaged. Among involved households, 8,663 were successfully interviewed at a response rate of 99%. The dependent variables measured in this study were improved drinking water sources and sanitation facilities. Due to the nested nature of DHS data, multilevel binary logistic regression analysis was done using Stata-16. Results: The majority (72.62%) of household heads were men, and 69.47% of participants were from rural areas. Close to half (47.65%) of study participants did not have any form of formal education, while the lowest proportion (9.89%) of them had higher education. Approximately 71.74 and 27.45% of the households have accessed improved water sources and sanitation, respectively. Based on the final model results, wealth index, educational status, and having a television individual-level variables while community-level poverty, community-level education, community-level media exposure, and place of residence were statistically significant predictors of getting improved water source and sanitation. Conclusion: The level of access to improved water sources is moderate but it lacks progress, while access to improved sanitation was lower. Based on these findings, great improvements should be made in providing access to an improved water source and sanitation facilities in Ethiopia. Based on these findings, great improvements should be made in providing access to improved water source and sanitation facilities in Ethiopia.


Subject(s)
COVID-19 , Drinking Water , Male , Humans , Female , Sanitation , Ethiopia , Multilevel Analysis , Pandemics , Demography
4.
Environ Sci Technol ; 57(8): 3248-3259, 2023 02 28.
Article in English | MEDLINE | ID: covidwho-2285743

ABSTRACT

COVID-19 pandemic-related building restrictions heightened drinking water microbiological safety concerns post-reopening due to the unprecedented nature of commercial building closures. Starting with phased reopening (i.e., June 2020), we sampled drinking water for 6 months from three commercial buildings with reduced water usage and four occupied residential households. Samples were analyzed using flow cytometry and full-length 16S rRNA gene sequencing along with comprehensive water chemistry characterization. Prolonged building closures resulted in 10-fold higher microbial cell counts in the commercial buildings [(2.95 ± 3.67) × 105 cells mL-1] than in residential households [(1.11 ± 0.58) × 104 cells mL-1] with majority intact cells. While flushing reduced cell counts and increased disinfection residuals, microbial communities in commercial buildings remained distinct from those in residential households on the basis of flow cytometric fingerprinting [Bray-Curtis dissimilarity (dBC) = 0.33 ± 0.07] and 16S rRNA gene sequencing (dBC = 0.72 ± 0.20). An increase in water demand post-reopening resulted in gradual convergence in microbial communities in water samples collected from commercial buildings and residential households. Overall, we find that the gradual recovery of water demand played a key role in the recovery of building plumbing-associated microbial communities as compared to short-term flushing after extended periods of reduced water demand.


Subject(s)
COVID-19 , Drinking Water , Microbiota , Humans , Sanitary Engineering , Drinking Water/microbiology , Water Supply , RNA, Ribosomal, 16S/genetics , Pandemics , Water Quality , Water Microbiology
5.
Int J Environ Res Public Health ; 20(2)2023 Jan 05.
Article in English | MEDLINE | ID: covidwho-2232980

ABSTRACT

COVID-19 has changed the world since 2020, and the field of water specifically, boosting scientific productivity (in terms of published articles). This paper focuses on the influence of COVID-19 on scientific productivity with respect to four water variables: (i) wastewater, (ii) renewable water resources, (iii) freshwater withdrawal, and (iv) access to improved and safe drinking water. The field's literature was firstly reviewed, and then the maps were built, emphasizing the strong connections between COVID-19 and water-related variables. A total of 94 countries with publications that assess COVID-19 vs. water were considered and evaluated for how they clustered. The final step of the research shows that, on average, scientific productivity on the water topic was mostly conducted in countries with lower COVID-19 infection rates but higher development levels as represented by gross domestic product (GDP) per capita and the human development index (HDI). According to the statistical analysis, the water-related variables are highly significant, with positive coefficients. This validates that countries with higher water-related values conducted more research on the relationship with COVID-19. Wastewater and freshwater withdrawal had the highest impact on the scientific productivity with respect to COVID-19. Access to safe drinking water becomes insignificant in the presence of the development parameters.


Subject(s)
COVID-19 , Drinking Water , Humans , Wastewater , COVID-19/epidemiology , Publications , Gross Domestic Product
6.
Environ Health ; 22(1): 9, 2023 01 20.
Article in English | MEDLINE | ID: covidwho-2196303

ABSTRACT

BACKGROUND: Recent studies linking low levels of nitrate in drinking water to colorectal cancer have raised public concerns over nitrate contamination. The aim of this study was to analyze the media discourse on the potential human health hazard of nitrates in drinking water in a high-income country with a large livestock industry: New Zealand (NZ). METHODS: Searches of media sources ("major newspapers") held by the Factiva database for the NZ setting in the five-year period 17 December 2016 to 20 December 2021. RESULTS: The largest number of media items was observed for 2017 (n = 108), the year of a NZ general election, with a notable decrease in 2020 (n = 20) that was likely due to the Covid-19 pandemic, which dominated health media. However, the percentage of these media items with a health focus steadily increased over time, from 11.1% of all articles in 2017 to 51.2% in 2021. The most commonly mentioned health hazard was colorectal cancer, followed by methemoglobinemia. The temporal pattern of media items suggests that the release of scientific studies and scholarly blogs was associated with the publication of subsequent media items. Major stakeholders involved in the discourse included representatives of local and central government, environmental and recreational interest groups, researchers, local residents, agricultural interest groups, and health organizations. Maori (Indigenous New Zealanders) values or perspectives were rarely mentioned. CONCLUSIONS: Analysis of major newspapers for a five-year period indicated that a wide range of expert comment and opinions were made available to the public and policy makers on the issue of nitrates in water. While many different stakeholder views were captured in the media discourse, there is scope for the media to better report the views of Maori on this topic. There is also a need for articles detailing the health issues to also refer to the environmental, recreational, and cultural aspects of protecting water quality to ensure that the public, policy makers, and regulators are aware of co-benefits.


Subject(s)
COVID-19 , Colorectal Neoplasms , Drinking Water , Humans , Nitrates/adverse effects , Nitrates/analysis , Drinking Water/analysis , Pandemics
7.
Environ Sci Technol ; 56(23): 16929-16939, 2022 Dec 06.
Article in English | MEDLINE | ID: covidwho-2133140

ABSTRACT

Acetaminophen is widely used to treat mild to moderate pain and to reduce fever. Under the worldwide COVID-19 pandemic, this over-the-counter pain reliever and fever reducer has been drastically consumed, which makes it even more abundant than ever in municipal wastewater and drinking water sources. Chlorine is the most widely used oxidant in drinking water disinfection, and chlorination generally causes the degradation of organic compounds, including acetaminophen. In this study, a new reaction pathway in the chlorination of acetaminophen, i.e., oxidative coupling reactions via acetaminophen radicals, was investigated both experimentally and computationally. Using an ultraperformance liquid chromatograph coupled to an electrospray ionization-triple quadrupole mass spectrometer, we detected over 20 polymeric products in chlorinated acetaminophen samples, some of which have structures similar to the legacy pollutants "polychlorinated biphenyls". Both C-C and C-O bonding products were found, and the corresponding bonding processes and kinetics were revealed by quantum chemical calculations. Based on the product confirmation and intrinsic reaction coordinate computations, a pathway for the formation of the polymeric products in the chlorination of acetaminophen was proposed. This study suggests that chlorination may cause not only degradation but also upgradation of a phenolic compound or contaminant.


Subject(s)
COVID-19 , Disinfectants , Drinking Water , Water Pollutants, Chemical , Water Purification , Humans , Disinfection , Chlorine , Drinking Water/chemistry , Acetaminophen , Molecular Weight , Pandemics , Water Pollutants, Chemical/chemistry , Halogenation , Pain , Disinfectants/chemistry
8.
MMWR Morb Mortal Wkly Rep ; 71(47): 1496-1502, 2022 Nov 25.
Article in English | MEDLINE | ID: covidwho-2145602

ABSTRACT

Dracunculiasis (Guinea worm disease), caused by the parasite Dracunculus medinensis, is acquired by drinking water containing small crustacean copepods (water fleas) infected with D. medinensis larvae. Recent evidence suggests that the parasite also appears to be transmitted by eating fish or other aquatic animals. About 1 year after infection, the worm typically emerges through the skin on a lower limb of the host, causing pain and disability (1). No vaccine or medicine is available to prevent or treat dracunculiasis. Eradication relies on case containment* to prevent water contamination and other interventions to prevent infection, including health education, water filtration, treatment of unsafe water with temephos (an organophosphate larvicide), and provision of safe drinking water (1,2). CDC began worldwide eradication efforts in October 1980, and in 1984 was designated by the World Health Organization (WHO) as the technical monitor of the Dracunculiasis Eradication Program (1). In 1986, with an estimated 3.5 million cases† occurring annually in 20 African and Asian countries§ (3), the World Health Assembly called for dracunculiasis elimination. The Guinea Worm Eradication Program (GWEP),¶ led by The Carter Center and supported by partners that include WHO, UNICEF, and CDC, began assisting ministries of health in countries with endemic disease. In 2021, a total of 15 human cases were identified and three were identified during January-June 2022. As of November 2022, dracunculiasis remained endemic in five countries (Angola, Chad, Ethiopia, Mali, and South Sudan); cases reported in Cameroon were likely imported from Chad. Eradication efforts in these countries are challenged by infection in animals, the COVID-19 pandemic, civil unrest, and insecurity. Animal infections, mostly in domestic dogs, some domestic cats, and in Ethiopia, a few baboons, have now surpassed human cases, with 863 reported animal infections in 2021 and 296 during January-June 2022. During the COVID-19 pandemic all national GWEPs remained fully operational, implementing precautions to ensure safety of program staff members and community members. In addition, the progress toward eradication and effectiveness of interventions were reviewed at the 2021 and 2022 annual meetings of GWEP program managers, and the 2021 meeting of WHO's International Commission for the Certification of Dracunculiasis Eradication. With only 15 human cases identified in 2021 and three during January-June 2022, program efforts appear to be closer to reaching the goal of eradication. However, dog infections and impeded access because of civil unrest and insecurity in Mali and South Sudan continue to be the greatest challenges for the program. This report describes progress during January 2021-June 2022 and updates previous reports (2,4).


Subject(s)
COVID-19 , Dracunculiasis , Drinking Water , Humans , Animals , Cats , Dogs , Dracunculiasis/epidemiology , Dracunculiasis/prevention & control , Dracunculiasis/veterinary , Pandemics , Disease Eradication
9.
PLoS One ; 17(10): e0276553, 2022.
Article in English | MEDLINE | ID: covidwho-2089435

ABSTRACT

INTRODUCTION: So far, shreds of evidence have shown that COVID-19 related hospitalization, serious outcomes, and mortality were high among individuals with chronic medical conditions. However, strict compliance with basic public health measures such as hand washing with soap, social distancing, and wearing masks has been recommended and proven effective in preventing transmission of the infection. Therefore, this study aimed to determine the level of compliance with COVID-19 preventive measures and identify its predictors among patients with common chronic diseases in public hospitals of Southern Ethiopia by applying the proportional odds model. METHODS: A facility-based cross-sectional study was employed in public hospitals of Southern Ethiopia between February and March 2021. Using a systematic random sampling technique, 419 patients with common chronic diseases were recruited. Data were collected using an Open Data Kit and then submitted to the online server. The proportional odds model was employed, and the level of significance was declared at a p-value of less than 0.05. RESULTS: This study revealed that 55.2% (95%CI: 50.4%-59.9%) of the study participants had low compliance levels with COVID-19 preventive measures. The final proportional odds model identified that perceived susceptibility (AOR: 0.91, 95%CI: 0.84, 0.97), cues to action (AOR: 0.89, 95%CI: 0.85, 0.94), having access to drinking water piped into the dwelling (AOR: 0.52, 95%CI: 0.32, 0.84), having no access to any internet (AOR: 0.62, 95%CI: 0.42, 0.92), having no functional refrigerator (AOR: 2.17, 95%CI: 1.26, 3.74), and having poor knowledge (AOR: 1.42, 95%CI: 1.02, 1.98) were the independent predictors of low compliance level with COVID-19 preventive measures. CONCLUSION: In the study area, more than half of the participants had low compliance levels with COVID-19 preventive measures. Thus, the identified factors should be considered when designing, planning, and implementing new interventional strategies, so as to improve the participants' compliance level.


Subject(s)
COVID-19 , Drinking Water , Humans , COVID-19/epidemiology , COVID-19/prevention & control , Cross-Sectional Studies , Ethiopia/epidemiology , Soaps , Chronic Disease
10.
Environ Monit Assess ; 194(11): 823, 2022 Sep 23.
Article in English | MEDLINE | ID: covidwho-2041295

ABSTRACT

Leather industry is the second largest export-earning sector of Pakistan. However, because of poor waste management, this industry has been continuously polluting the environment. In this paper, the impact of tanneries on the groundwater quality of Kasur city (i.e., the second largest leather producing city) is examined. The study is conducted in the following three phases: (I) water samples collection, (II) determination of physio-chemical properties, and (III) application of data mining techniques. In phase I, groundwater samples were collected from various sources such as hand pumps, motor pumps, and tube wells. In phase II, several physio-chemical properties such as (i) total dissolved solids (TDS), (ii) pH, (iii) turbidity, (iv) electrical conductivity (EC), (v) total hardness (TH), (vi) total alkalinity (TA), (vii) nitrates, (viii) chromium, (ix) fluoride, and (x) chloride were estimated. The estimated values of all these foregoing parameters are then compared with the Punjab Environmental Quality Standards for Drinking Water (PEQSDW). In phase III, principle component analysis and cluster analysis of the estimated parameters were performed to elucidate the relation between various parameters and to highlight the highly vulnerable sites, respectively. The results exhibit that most of the sampling collections sites are at the threshold of losing quality water. Moreover, it is also found that Mangal Mandi carries the worst groundwater quality among all sampling locations. Overall, it is concluded that serious attention is due from the water and wastewater authorities to further investigate and monitor the groundwater quality of Kasur before the country strikes with another pandemic after COVID-19.


Subject(s)
COVID-19 , Drinking Water , Groundwater , Water Pollutants, Chemical , Chlorides/analysis , Chromium/analysis , Drinking Water/analysis , Environmental Monitoring/methods , Fluorides/analysis , Groundwater/chemistry , Humans , Nitrates/analysis , Pakistan , Wastewater/analysis , Water Pollutants, Chemical/analysis , Water Quality
11.
Environ Toxicol Chem ; 41(10): 2613-2621, 2022 10.
Article in English | MEDLINE | ID: covidwho-2027344

ABSTRACT

Increased disinfection efforts in various parts of China, including Hong Kong, to prevent the spread of the novel coronavirus may lead to elevated concentrations of disinfectants in domestic sewage and surface runoff in Hong Kong, generating large quantities of toxic disinfection byproducts. Our study investigated the presence and distribution of four trihalomethanes (THMs), six haloacetic acids (HAAs), and eight nitrosamines (NAMs) in rivers and seawater in Hong Kong. The concentrations of THMs (mean concentration: 1.6 µg/L [seawater], 3.0 µg/L [river water]), HAAs (mean concentration: 1.4 µg/L [seawater], 1.9 µg/L [river water]), and NAMs (mean concentration: 4.4 ng/L [seawater], 5.6 ng/L [river water]) did not significantly differ between river water and seawater. The total disinfection byproduct content in river water in Hong Kong was similar to that in Wuhan and Beijing (People's Republic of China), and the total THM concentration in seawater was significantly higher than that before the COVID-19 pandemic. Among the regulated disinfection byproducts, none of the surface water samples exceeded the maximum index values for THM4 (80 µg/L), HAA5 (60 µg/L), and nitrosodimethylamine (100 ng/L) in drinking water. Among the disinfection byproducts detected, bromoform in rivers and seawater poses the highest risk to aquatic organisms, which warrants attention and mitigation efforts. Environ Toxicol Chem 2022;41:2613-2621. © 2022 SETAC.


Subject(s)
COVID-19 , Disinfectants , Drinking Water , Water Pollutants, Chemical , Water Purification , Dimethylnitrosamine , Disinfectants/analysis , Disinfection , Halogenation , Hong Kong , Humans , Pandemics , Pilot Projects , Sewage , Trihalomethanes/analysis , Water Pollutants, Chemical/analysis
17.
Int J Environ Res Public Health ; 19(11)2022 05 25.
Article in English | MEDLINE | ID: covidwho-1924229

ABSTRACT

The WHO/UNICEF Joint Monitoring Program (JMP) for Water Supply, Sanitation and Hygiene (WASH) produces global estimates of the real situation of access to water, sanitation and hygiene services, and sanitation and hygiene in households, educational institutes and health care facilities; however it is lacking data on schools in Kazakhstan. Thus, the aim of this research was to assess access to WASH in schools of urban area in Kazakhstan. The study was conducted in seven schools of Central Kazakhstan during the COVID-19 pandemic and restrictive measures. Three data collection methods were used: a questionnaire for administrative staff, a questionnaire for parents and observation. Parents of offline study pupils (only second and third grades due to the pandemic) were included in the survey. Students had access to in-building toilets in all schools connected to the centralized sewer. The number of school toilets varied from 7 (KAZ200085) to 61 (KAZ200089). The average amount of toilets was 28.08 ± 16.97. Only two out of seven schools complied with the requirements of Kazakhstan national sanitary standards for the ratio of school toilets to the number of students. From the questionnaire with the school administrations, it was defined that the primary source of drinking water was the public water supply. All schools regularly disinfect and check the water supply system. At the same time, the results also revealed discrepancies in the answers between administration and parents (2.6% of parents showed that their children have rare access to drinking water), and insufficient monitoring of implementation of WASH services. This study also confirmed that the full provision of access to water and water services in the structure of educational institutions solves several SDG targets.


Subject(s)
COVID-19 , Drinking Water , COVID-19/epidemiology , Child , Humans , Hygiene , Kazakhstan/epidemiology , Pandemics , Sanitation , Schools , Water Supply
18.
Toxicology ; 477: 153254, 2022 07.
Article in English | MEDLINE | ID: covidwho-1915038

ABSTRACT

MA-T (Matching Transformation System®) is a proprietary chemical mixture for on-demand production of aqueous chlorine dioxide that is used for the treatment of oral malodor. MA-T is also an effective disinfectant against at least 39 pathological microorganisms, including severe acute respiratory syndrome coronavirus 2, and therefore may be useful as a disinfectant mouthwash to prevent the spread of infection. Accidental ingestion is the putative worst hazard scenario associated with mouthwash use; therefore, here we investigated the safety of MA-T ingestion in mice. Mice were provided drinking water containing 0-3000 µg/ml MA-T for 7 days followed by non-spiked drinking water for an additional 14 days. At day 7, mice ingesting 1000 or 3000 µg/ml MA-T showed significantly decreased body weight and significantly increased liver, kidney, and heart tissue injury biomarkers compared with control. However, at 14 days after stopping MA-T ingestion, body weight and tissue injury biomarkers had returned to normal. Histological analysis revealed that MA-T-induced injuries in liver, kidney, spleen, stomach, duodenum, colon, and rectum had also recovered at 14 days after stopping MA-T ingestion; however, mild vascular endothelial injuries remained in heart, jejunum, and ileum in the worst-case scenario. Taken together, MA-T may be potentially safety for further development as a disinfectant mouthwash by risk management, such as placing a caution of the label and adding a distinctive flavor.


Subject(s)
COVID-19 , Disinfectants , Drinking Water , Animals , Body Weight , Disinfectants/toxicity , Eating , Mice , Mouthwashes/toxicity
19.
Huan Jing Ke Xue ; 43(6): 2996-3004, 2022 Jun 08.
Article in Chinese | MEDLINE | ID: covidwho-1876194

ABSTRACT

The seasonal variation and spatial distribution of pharmaceuticals in typical drinking water sources in the middle reaches of the Yangtze River were analyzed using the solid-phase extraction and high-performance liquid chromatography-tandem mass spectrometry methods. Combined with the risk entropy method, the corresponding ecological risks for aquatic organisms were evaluated. The results showed that 80% of the target pharmaceuticals were detected in the drinking water sources, with average concentrations of 0.07-13.00 ng·L-1. The concentrations of the target pharmaceuticals were lower than or comparable with those in other drinking water sources reported in China. The spatiotemporal distribution of different pharmaceuticals varied. Generally, the detection level in winter was higher than that in summer, and there was no significant difference between that upstream and that downstream. This might be mainly attributed to seasonal/regional use and emissions of the pharmaceuticals, the impact of flow rate on dilution, and the impact of temperature on biodegradation. Compared with those before the COVID-19 epidemic, the detection concentrations of the target pharmaceuticals were relatively low. The reason for this might be that the prevention and control of the epidemic reduced the use and emission of the pharmaceuticals to a certain extent, and the high rainfall and runoff strengthened the dilution of water flow. The target pharmaceuticals, especially antibiotics, posed medium or low risks to aquatic organisms (especially algae). Considering the ecological risks and genotoxicity of pharmaceuticals and the potential risks of antibiotic-resistant genes, it is suggested to strengthen the investigation, evaluation, treatment, and control of pharmaceuticals in the water environment.


Subject(s)
COVID-19 , Drinking Water , Water Pollutants, Chemical , Anti-Bacterial Agents/analysis , Aquatic Organisms , China , Drinking Water/analysis , Environmental Monitoring/methods , Humans , Pharmaceutical Preparations , Risk Assessment , Water Pollutants, Chemical/analysis
20.
Comput Math Methods Med ; 2022: 3009589, 2022.
Article in English | MEDLINE | ID: covidwho-1832669

ABSTRACT

Objective: This study is aimed at investigating the epidemiology and risk factors of acute hemorrhagic conjunctivitis (pinkeye) in Huangshi Port District of Huangshi City. Methods: A total of 593 cases of acute hemorrhagic conjunctivitis from January 2019 to December 2021 were selected as the observation group. The epidemiological characteristics (age of onset, season, occupation, clinical manifestations, and etiological characteristics) were analyzed. A total of 425 healthy subjects (nonacute hemorrhagic conjunctivitis) were selected as the control group. The general data of the two groups were compared, and the risk factors affecting the occurrence of acute hemorrhagic conjunctivitis were analyzed by logistic regression. Results: The onset age of acute hemorrhagic conjunctivitis was mainly concentrated in 0-20-year-old and 60-year-old age groups, and the onset season was mainly concentrated in April to August, with the highest incidence in May. The proportions of middle school students and workers in patients with acute hemorrhagic conjunctivitis were higher than those of other occupations (both P < 0.05). Ocular conjunctival congestion, tingling, and foreign body sensation were the main clinical manifestations of patients with acute hemorrhagic conjunctivitis. Among the 593 conjunctival swab samples collected in this study, the positive rates of HEV70 and CVA24v were higher than those of adenovirus nucleic acid (both P < 0.05). The proportion of people aged ≤40 years old, male, working outdoors, using potable water equipment, contact history of patients with acute conjunctivitis, history of chemical substances entering eyes, combined with immune system diseases, and public toilet utilization rate ≥ 1 times/d in the observation group was higher than that in the control group (all P < 0.05), and the proportion of people washing hands before eating and after toilet was lower than that in the control group (P < 0.05). Multiple logistic regression analysis showed that working place outdoors, use of potable water equipment, contact history of patients with acute conjunctivitis (all P < 0.05), and use of public toilets ≥ once a day were risk factors for the occurrence of acute hemorrhagic conjunctivitis, and washing hands before eating and after toilet was a protective factor (P < 0.05). Conclusion: The onset age of acute hemorrhagic conjunctivitis was mainly concentrated in 0-20-year-old and 60-year-old age; the onset season was mainly concentrated in summer and autumn; adenovirus is the main pathogenic bacteria; ocular conjunctivitis congestion, tingling, and foreign body sensation were the main clinical manifestations; working place outdoors, use of potable water equipment, contact history of patients with acute conjunctivitis (all P < 0.05), and use of public toilets ≥ once a day were risk factors for the occurrence of acute hemorrhagic conjunctivitis, while washing hands before eating and after toilet was a protective factor.


Subject(s)
Conjunctivitis, Acute Hemorrhagic , Conjunctivitis , Drinking Water , Foreign Bodies , Adolescent , Adult , Child , Child, Preschool , Conjunctivitis/epidemiology , Conjunctivitis, Acute Hemorrhagic/epidemiology , Conjunctivitis, Acute Hemorrhagic/microbiology , Factor Analysis, Statistical , Humans , Infant , Infant, Newborn , Male , Risk Factors , Young Adult
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